Trial | NCT00638170  Report issue

Title

Cranberry Juice in the Prevention of Urinary Tract Infections in Children
The Efficacy of Cranberry Juice in the Prevention of Urinary Tract Infections in Children - Randomized, Placebo Controlled Multi-Center Study

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    cranberry ...

  • Study Participants

    262
The objective of the study is to determine whether recurrences of urinary tract infection in children can be prevented with cranberry juice.
Five percent of children have at least one UTI episode and 30% of these episodes recur. Recurrences and the risk of renal damage are indications for long term antimicrobial prophylaxis, but emerging antimicrobial resistance underlines the need for alternatives. The bacteria causing urinary tract infection arise from the stools. Dietary changes can alter the balance of faecal bacteria. Vaccinium berries and products containing lactobacilli have been shown to act against the coliform bacteria that cause most urinary tract infections. In our previous study cranberry juice was effective in preventing symptomatic recurrences of urinary tract infections in women. The objective of our study is to determine whether recurrences of urinary tract infection in children can be prevented with cranberry juice.
Study Started
May 31
2001
Primary Completion
Feb 28
2009
Study Completion
Feb 28
2009
Last Update
Feb 16
2009
Estimate

Biological Cranberry juice

5 ml/kg up to 300 ml, 1-2 doses daily for six months

Biological Placebo juice

5 ml/kg up to 300 ml, 1-2 doses daily for six months

A Active Comparator

Cranberry juice

B Placebo Comparator

Placebo juice

Criteria 

Inclusion Criteria:

Urinary Tract Infection 0-2 months priorly

Exclusion Criteria:

Antibiotic Prophylaxis
No Results Posted