Trial | NCT00628940  Report issue

Official Title

PET Imaging of High-grade Glioma Using 18F-fluoromethylcholine: a Tool for the Early Detection of Tumour Recurrence After Combined Radiochemotherapy?

  • Phase

    Phase 1

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    90
The aim of the study is to define preferential sites of tumour recurrence by observing tracer uptake in the tumour in sequential PET images with 18F-fluoromethylcholine (and perfusion MR, see also below). Changes in the intensity of the tracer uptake in the tumour during and after the course of radiotherapy will be correlated with the site of tumour recurrence as will be assessed by conventional MRI. In due time, these results must enable clinicians to change their therapeutic approach of high-grade glioma.
Study Started
Jan 12
2010
Primary Completion
Mar 14
2017
Study Completion
Mar 22
2018
Last Update
May 18
2018

Radiation PET images with 18F-fluoromethylcholine

sequential PET images with 18F-fluoromethylcholine

1 Experimental

18F-fluoromethylcholine

Criteria 

Inclusion Criteria:

18 years or older
patients with high-grade glioma who will undergo adjuvant radiochemotherapy after surgery

Exclusion Criteria:

low global performance state
pregnancy
lactation period
presence of pacemaker, vascular clips in the brain ,epidural electrodes, implanted hearing device, set of false theeth attached by means of magnetes, wig attached by means of metal clips
No Results Posted