Trial | NCT00535561  Report issue

Title

Iron Deficiency Anemia Can be an Indication for Treatment of Subclinical Hypothyroidism
Iron Deficiency Anemia Can be an Indication for Treatment of Subclinical Hypothyroidism: A Randomized, Double Blinded Study

  • Phase

    Phase 1

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    None
To determine whether iron deficiency anemia can be an indication for the treatment of subclinical hypothyroidism.
51 Patients presented to our university outpatient internal medicine clinic who are found to have iron deficiency anemia coexisting with subclinical hypothyroidism have been included in this study. Patients were randomly assigned to oral iron or oral iron plus levothyroxin therapy. The physician and the patients did not know who received oral iron only or oral iron plus levothyroxine treatment. Hematologic parameters as well as serum iron, ferritin and iron binding capacity were being measured at the beginning and 3 months after treatment in both groups.
Study Started
Jun 30
2007
Study Completion
Sep 30
2007
Last Update
Feb 17
2012
Estimate

Drug Ferrous sulfate tablets 325 mg, po, TID

Drug Ferrous sulfate plus levothyroxine

Combination of ferrous sulfate tablet 325mg plus levothyroxine tablet 25 micrograms, po, TID

1 Active Comparator

Oral iron treatment only- for iron deficiency anemia and subclinical hypothyroidism coexisting patients

2 Active Comparator

Oral iron plus levothyroxine treatment- for iron deficiency anemia and subclinical hypothyroidism coexisting patients

Criteria 

Inclusion Criteria:

Clinical diagnosis and laboratory confirmation of iron deficiency anemia and subclinical hypothyroidism
Must be able to swallow tablets

Exclusion Criteria:

Multifactorial anemia or anemia due to other reasons
Iron deficiency anemia requiring urgent intervention- cardiac ischemia, severe anemia, GI or GU losses due to malignancy and or acute/subacute big loses by respiratory, Gİ, GU, etc. system
Prior thyroid disorder and/or treatment history
Presence of any other co-morbid disease like renal insufficiency/ failure, coronary heart disease, hypertension, diabetes mellitus, any endocrine system disease other than subclinical hypothyroidism
No Results Posted