Trial | NCT00430547  Report issue

Official Title

Thyroid-Associated Ophthalmopathy Subtypes and Orbital Antibodies

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    carbimazole ...

  • Study Participants

    60
The purpose of this study is to determine whether radioactive iodine, as compared to anti-thyroid medications, is a risk factor for the development or progression of thyroid-associated ophthalmopathy in patients with hyperthyroidism due to Graves' disease. The other aim of this study is to determine the incidence of the various ophthalmopathy subtypes and the utility of orbital antibodies in the diagnosis, classification and monitoring of patients with thyroid-associated ophthalmopathy.
Study Started
Aug 31
2003
Study Completion
Jan 31
2006
Last Update
Feb 02
2007
Estimate

Drug Carbimazole, radio-active iodine (I131)

Criteria 

Inclusion Criteria:

Graves' disease diagnosed in the last 3 months, regardless of the presence of ophthalmopathy

Exclusion Criteria:

Pre-existing eye disease: e.g. orbital surgery, orbital irradiation or significant loss of vision
Age < 18 years
Inability to consent to participation in the study
Pregnancy
History of radio-active iodine therapy
No Results Posted