Trial | NCT00376636  Report issue

Title

Phase IIa Safety and Efficacy Study of SPP635 in Mild to Moderate Hypertension
A Phase IIa, Double-Blind, Placebo-Controlled, Randomised, Parallel-Design, Four-Week Study to Investigate the Safety and Efficacy of the Oral Renin Inhibitor SPP635 Once Daily in Patients With Mild to Moderate Hypertension

  • Phase

    Phase 2

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    spp635 ...

  • Study Participants

    35
This study is conducted to investigate the effect of the oral renin inhibitor SPP635 on blood pressure in patients with mild to moderate hypertension.
Renin-Angiotensin system blockade is a well established target for treatment of high blood pressure. Blocking the system at the initial step, however, is a rather new concept that could only be implemented very recently through the availability of novel, oral, renin inhibitors. This study investigates the safety and efficacy of a novel oral renin inhibitor, SPP635.
Study Started
Oct 31
2006
Study Completion
May 31
2007
Last Update
Oct 30
2007
Estimate

Drug SPP635 (drug)

Criteria 

Inclusion Criteria:

male or female patients with mild to moderate hypertension

Exclusion Criteria:

female patients of child-bearing potential or breast-feeding
No Results Posted