Title
Retrograde Intrarenal Stone Surgery - A Method of Treating the ESWL Resistant Kidney Stone
RIRS - A Method of Treating the ESWL Resistant Kidney Stone
Phase
Phase 2Lead Sponsor
Fredericia HospitalStudy Type
InterventionalStatus
Unknown statusIndication/Condition
Kidney Stone UreteroscopyIntervention/Treatment
isoprenaline ...Study Participants
10Is it possible to decrease the intrarenal pressure in the kidney during endoscopic management of kidney stone by topical administration of drugs? In order to secure fewer complications in ureteroscopic operations the pharmacological agent isoproterenol is tested on pigs and human to determine its potential of lowering intrarenal pressure.
Inclusion Criteria: Indication for RIRS procedure Age > 18 years Normotensive Capable of understanding information given Exclusion Criteria: Previous myocardiac infarct Daily use of alpha- og beta- blocking medicine og calcium antagonists Use of NSAID the last 2 days Stone in the ureter Declared Known malignant disease in urinary tract Bladder disease Nephrostomies inserted JJ-catheters inserted Prisoners Pregnant Nursing mothers