Title
Effects of Ketamine On Precipitated Opioid Withdrawal Under General Anaesthesia
Phase
Phase 4Lead Sponsor
Vilnius UniversityStudy Type
InterventionalStatus
Completed No Results PostedIndication/Condition
Opiate DependenceIntervention/Treatment
ketamine ...Study Participants
60The purpose of this study is to determine whether low-dose ketamine infusion is effective in suppressing the symptoms of opiate withdrawal during rapid opiate antagonist induction (RAI).
Inclusion Criteria: Diagnosed opiate dependence according to ICD 10 and/or DSM 4; Duration of substance abuse more than 1 year No or minor co-morbidities; Grade I-II according to physical status classification system of American Society of Anesthesiologists. Exclusion Criteria: Current history of long acting opiate or poly-substance abuse; Acute medical or surgical condition; Pregnancy; Breastfeeding.