Title
Cosopt Versus Xalatan
Phase
Phase 4Lead Sponsor
PRN Pharmacuetical Research Network, LLCStudy Type
InterventionalStatus
Completed No Results PostedIndication/Condition
Open-Angle Glaucoma Ocular HypertensionIntervention/Treatment
dorzolamide latanoprost timolol ...Study Participants
NoneTo compare the 24-hour efficacy and safety, measured every three hours, of the dorzolamide/timolol fixed combination given twice daily versus latanoprost and placebo each given once daily.
Inclusion Criteria: adults with primary open-angle, pigmentary, or exfoliation glaucoma, or ocular hypertenstion intraocular pressure should be 22 to 30 mm Hg inclusive on timolol BID at the 08:00 H ETDRS visual acuity must be 1.0 or better in both eyes Exclusion Criteria: any contraindications to study medications any anticipated change in systemic hypertensive therapy during the trial