Trial | NCT00262587  Report issue

Official Title

Elite Sport and Development of Asthma

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    fluticasone ...

  • Study Participants

    18
International studies have shown that elite athletes have a high prevalence of respiratory symptoms and asthma as compared to normal subjects. It is unclear whether the increased prevalence of asthma in elite athletes reflects "traditional asthma" or whether it is a special form of "sports asthma". The treatment of elite athletes with asthma seems to vary widely, and only a few studies have focused on the treatment of elite athletes with asthma. Further knowledge of the pathogenesis of sports asthma would lead to a greater understanding and better treatment of the condition. This study will investigate the type of airway inflammation in elite athletes and examine the effect of treatment with inhaled steroids in combination with long-acting beta-agonists versus placebo in the same group.
Study Started
Sep 30
2005
Primary Completion
Dec 31
2008
Study Completion
Dec 31
2008
Last Update
May 16
2012
Estimate

Drug Seretide

Combination of inhaled corticosteroids (250 microgr) and inhaled long-acting beta2-agonists (25 microgr)

Drug Placebo

Inhaled sugar powder in a placebo inhaler

Placebo Placebo Comparator

Placebo inhaler (sugar powder)

Seretide Active Comparator

Seretide inhaler

Criteria 

Inclusion Criteria:

Elite athletes
Informed consent
Doctor diagnosed asthma

Exclusion Criteria:

Current smoker or more than 10 pack-years
Pregnancy, breast feeding or planning pregnancy during the study.
ICS within the last 4 weeks prior to visit 1.
No Results Posted