Trial | NCT00238862  Report issue

Title

Treatment of PED With AMT and Autologous Serum
Efficacy of Amniotic Membrane Transplantation and Autologous Serum in Treatment of Persistent Epithelial Defects

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    180
Patients with persistent corneal epithelial defects who have not responded to conventional therapy will be randomized to treatment with either amniotic membrane transplantation or autologous serum 20%. Outcome measures will be (1) presence or absence of complete re-epithelialization within 28 days and (2) retention of intact epithelium for at least 90 days.
Study Started
Oct 31
2005
Study Completion
Sep 30
2006
Last Update
Dec 02
2021

Procedure Amniotic membrane transplantation

Drug Autologous serum/BSS 20%

Criteria 

Inclusion Criteria:

Corneal epithelial defect of more than 14 days that has not responded to conventional therapy

Exclusion Criteria:

Under age 18
Pregnant/lactating females
Patients with hemoglobin levels < 12 mg/ml
Patients with limbal stem cell deficiency
No Results Posted