Trial | NCT00226837  Report issue

Official Title

Quantifying Nitrous Oxide Effect on Depth of Anaesthesia Using Theoretically Based Time Series Modelling

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    60
Our hypothesis is that a new method of depth of anaesthesia monitoring, using theoretically based time series modelling will result in improved ability to determine nitrous oxide anaesthetic effect
We randomised patients to 0% 33% or 66% nitrous oxide during sevoflurane induction and measured anesthetic endpoints.
Study Started
Aug 31
2004
Primary Completion
Aug 31
2005
Study Completion
Aug 31
2005
Last Update
Feb 05
2009
Estimate

Drug Nitrous oxide

nitrous oxide by inhalation during induction

  • Other names: No other names were used

1 Placebo Comparator

0% nitrous oxide

2 Active Comparator

33% nitrous oxide

3 Active Comparator

66% nitrous oxide

Criteria 

Inclusion Criteria:

Aged 18 years or older
Presenting for surgery under general anaesthesia

Exclusion Criteria:

Poor English language comprehension
Risk of reflux
Epilepsy or other EEG abnormality
No Results Posted