Trial | NCT00224094  Report issue

Title

A Comparison of Patch vs. Pill Estrogen Therapy on Testosterone Levels and Thyroid Tests in Menopausal Women
A Comparison of Transdermal vs. Oral Estrogen Replacement Therapy on Androgen Levels and Thyroid Function in Naturally Menopausal Women

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    27
This study compares the effects of 12 weeks of treatment with transdermal versus oral estrogen therapy on testsoterone levels and thyroid tests in healthy, naturally menopausal women.
Study Started
Jan 31
2002
Primary Completion
May 31
2003
Last Update
Oct 15
2012
Estimate

Drug Premarin® (oral) vs. Alora® (transdermal)

Sequence A Experimental

Oral ERT then transdermal ERT

Sequence B Experimental

Transdermal ERT then oral ERT

Criteria 

Inclusion Criteria:

Healthy
Naturally menopausal women
Aged 42-70 years
Currently using combination estrogen-progestin replacement therapy

Exclusion Criteria:

Women with contraindications to HRT use, including:Unexplained vaginal bleeding, liver disease, breast or endometrial cancer, venous thromboembolic events
Thyroid disease
Adrenal disease
No Results Posted