Trial | NCT00200226  Report issue

Official Title

Oral Misoprostol Before Endometrial Biopsy

  • Phase

    Phase 3

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    72
An endometrial biopsy involves a thin tube being passed through the cervix (opening of the uterus) to obtain a sample of the lining of the uterus. Sometimes there may be discomfort with this procedure especially if the cervix is not dilated or opened. Previous research has suggested that taking a drug called misoprostol may help the cervix to start to dilate or open. This study will see if misoprostol will help open the cervix for an endometrial biopsy, to lessen the discomfort and make the biopsy easier to perform.
Study Started
Feb 28
2003
Study Completion
Sep 30
2007
Last Update
Sep 21
2007
Estimate

Drug misoprostol

misoprostol 400mcg 12 hrs prior to procedure

  • Other names: Cytotec

Drug vitamin B6

Vitamin B6 50 mg orally 12 hrs prior to procedure

1 Placebo Comparator

Vitamin B6

2 Active Comparator

misoprostol

Criteria 

Inclusion Criteria:

women 19 years and older
planned endometrial biopsy

Exclusion Criteria:

known hypersensitivity or allery to prostaglandins
seizure disorder
liver disease
known abnormal liver function tests
pregnancy
No Results Posted