Trial | NCT00185146  Report issue

Title

Efficacy and Safety of Pactimibe in Patients With Atherosclerosis
Effect of Pactimibe on the Progression of Atherosclerosis as Measured by 2-D and 3-D Carotid Ultrasound

  • Phase

    Phase 2

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    pactimibe ...

  • Study Participants

    200
The effect of pactimibe on the reduction of atherosclerosis in the carotid artery will be assessed using carotid ultrasound
Study Started
Sep 30
2002
Study Completion
Aug 31
2005
Last Update
Mar 28
2007
Estimate

Drug Pactimibe

Criteria 

Inclusion Criteria:

Increased cardiovascular risk (i.e. history of myocardial infarction, stroke, diabetes mellitus, left ventricular hypertrophy)
Intima-media thickness greater than or equal to 0.8 mm as measured by ultrasonography
Negative pregnancy test for females

Exclusion Criteria:

Whole blood donation (greater than or equal to 450 ml) during the last three months before study start
Unstable angina, congestive heart failure or uncontrolled hypertension
Renal disease including nephrectomy and/or renal transplant
Hepatic disease or abnormal liver function parameters
Drug abuse or alcohol addiction
No Results Posted