Trial | NCT00163202  Report issue

Title

Comparative Atorvastatin Pleiotropic Effects
A Multicenter, Randomized Double-Blind Study Comparing The Pleiotropic Effects Of Atorvastatin 10 Mg And 80 Mg Over A 26-Week Period In Subjects With Coronary Atherosclerosis

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    atorvastatin ...

  • Study Participants

    330
The primary objective of the study is to evaluate the efficacy of atorvastatin 80 mg daily as compared to atorvastatin 10 mg daily in reducing C-reactive protein levels over a 26-week treatment period in subjects with documented coronary artery disease.
Study Started
Jun 30
2002
Study Completion
Aug 31
2005
Last Update
Feb 18
2021

Procedure Blood samples

Drug Atorvastatin

Criteria 

Inclusion Criteria:

Male or female subjects of age of majority to < 80 years
Subjects with LDL-C > 0.5 g/L (1.29 mmol/L) and < 1.5 g/L (3.87 mmol/L), TG < 4.00 g/L (4.56 mmol/L) and hs-CRP >1.5 mg/L and < 15 mg/L
Subjects with a documented coronary artery disease.

Exclusion Criteria:

Female subjects of childbearing potential without contraception
Subjects with secondary hyperlipidemia
Diabetic subjects receiving insulin
Subjects with a contra-indication to statin therapy.
No Results Posted