Trial | NCT00159107  Report issue

Title

Integrative Therapy in Alcoholism
Acamprosate and Integrative Behavior Therapy in the Outpatient Treatment of Alcohol Dependents

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    acamprosate ...

  • Study Participants

    371
The main aim of this project consists in the investigation of the interaction of behavior therapy and Acamprosate in the outpatient treatment of alcoholic patients in a randomized, prospective and (regarding study medication Acamprosate vs. Placebo) double blind design. A total of 371 patients has been randomly assigned immediately after detoxification to one of three different outpatient treat-ment conditions.
The objective of this multi-center study is to optimize the long-term treatment of patients with alcohol dependence. This investigation should contribute to the issue of effective relapse prevention. Each treatment condition is lasting 6 months: a) Behavior Group Therapy + Acamprosate, b) Behavior Group Therapy + Placebo and c) support and counseling + Acamprosate. Follow-up examinations carried out 3 and 6 months after the end of treatment.
Study Started
May 31
2003
Study Completion
Dec 31
2006
Last Update
Jan 30
2008
Estimate

Drug Placebo

Placebo

Drug Acamprosate

Acamprosate

Behavioral Integrative behavior therapy

Integrative behavior therapy

2 Experimental

Placebo +Integrative behavior therapy

3 Experimental

Acamprosate + treatment as usual

1 Experimental

Acamprosate + Integrative behavior therapy

Criteria 

Inclusion Criteria:

DSMIV criteria of alcoholism
Age between 25 and 60
Informed consent

Exclusion Criteria:

Residence outside of the catchment area
Legal reasons
Insufficient knowledge of the German language
Substance abuse or addiction other than alcohol or nicotine
Pregnancy
Serious physical illness
Organic brain disease
Contraindication to Acamprosate treatment
No Results Posted