Trial | NCT00126698  Report issue

Title

Prophylactic Antibiotics on Urethral Catheter Withdrawal
Use of Antibiotic Prophylaxis on Urethral Catheter Withdrawal: A Randomized Double-Blind Placebo-Controlled Trial

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    100
Urinary-tract infection (UTI) is the most common type of hospital-acquired infection (30% of all). The purpose of this study is to determine whether antibiotic prophylaxis for urinary catheter removal is useful at preventing catheter-associated urinary-tract infection.
Urinary-tract infection (UTI) is the most common type of hospital-acquired infection (30% of all). The researchers undertake a double-blind, placebo-controlled trial to assess the efficacy of single-dose therapy of trimethoprim-sulfamethoxazole or ciprofloxacin, versus placebo therapy in selected groups of surgical patients who had bladder drainage scheduled to last longer than 3 days.
Study Started
Jan 31
2005
Study Completion
Apr 30
2007
Last Update
Apr 19
2007
Estimate

Drug trimethoprim-sulfamethoxazole

Drug ciprofloxacin

Criteria 

Inclusion Criteria:

Urethral catheter in situ for at least 3 days (72h)

Exclusion Criteria:

Pregnancy
Impaired renal or hepatic function (serum creatinine > 150 mmol/l, serum transaminases > 75 IU/l)
Fever
Symptomatic urinary tract infection
Antibiotic use ≤ 48 hours before urinary catheter removal
Allergy to trimethoprim-sulfamethoxazole or ciprofloxacin
Urologic pathology
No Results Posted