V-Set Domain-Containing T-Cell Activation Inhibitor 1 D060907

Related MeSH Hierarchy (4)

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intercellular Signaling Peptides and Proteins » B7 Antigens » V-Set Domain-Containing T-Cell Activation Inhibitor 1

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » B7 Antigens » V-Set Domain-Containing T-Cell Activation Inhibitor 1

Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Surface » B7 Antigens » V-Set Domain-Containing T-Cell Activation Inhibitor 1

Chemicals and Drugs [D] » Biological Factors [D23] » Intercellular Signaling Peptides and Proteins » B7 Antigens » V-Set Domain-Containing T-Cell Activation Inhibitor 1

Description

A B7 antigen subtype that inhibits the costimulation of T-cell activation, proliferation, cytokine production and development of cytotoxicity. The over expression of this protein in a variety of tumor cell types suggests its role in TUMOR IMMUNE EVASION.   MeSH

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