Related MeSH Hierarchy (5)
Chemicals and Drugs [D] » Biological Factors [D23] » Intercellular Signaling Peptides and Proteins » B7 Antigens » B7-H1 Antigen
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intercellular Signaling Peptides and Proteins » B7 Antigens » B7-H1 Antigen
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » B7 Antigens » B7-H1 Antigen
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Immune Checkpoint Proteins » B7-H1 Antigen
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Surface » B7 Antigens » B7-H1 Antigen
Description
An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION. MeSH
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