Solid-Phase Synthesis Techniques D060327

Technology, Industry, and Agriculture [J] » Technology, Industry, and Agriculture [J01] » Technology » Technology, Pharmaceutical » Chemistry Techniques, Synthetic » Solid-Phase Synthesis Techniques

Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E] » Investigative Techniques [E05] » Chemistry Techniques, Synthetic » Solid-Phase Synthesis Techniques

Description

Techniques used to synthesize chemicals using molecular substrates that are bound to a solid surface. Typically a series of reactions are conducted on the bound substrate that results in either the covalent attachment of specific moieties or the modification of existing function groups. These techniques offer an advantage to those involving solution reactions in that the substrate compound does not have to be isolated and purified between the reaction steps.   MeSH

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