Related MeSH Hierarchy (5)
Phenomena and Processes [G] » Cell Physiological Phenomena [G04] » Endoplasmic Reticulum Stress » Unfolded Protein Response
Phenomena and Processes [G] » Chemical Phenomena [G02] » Biochemical Phenomena » Peptide Biosynthesis » Protein Biosynthesis » Protein Modification, Translational » Protein Processing, Post-Translational » Unfolded Protein Response
Phenomena and Processes [G] » Chemical Phenomena [G02] » Biochemical Phenomena » Protein Modification, Translational » Protein Processing, Post-Translational » Unfolded Protein Response
Phenomena and Processes [G] » Metabolism [G03] » Peptide Biosynthesis » Protein Biosynthesis » Protein Modification, Translational » Protein Processing, Post-Translational » Unfolded Protein Response
Phenomena and Processes [G] » Genetic Phenomena [G05] » Gene Expression Regulation » Protein Modification, Translational » Protein Processing, Post-Translational » Unfolded Protein Response
Description
A cellular response to environmental insults that cause disruptions in PROTEIN FOLDING and/or accumulation of defectively folded protein in the ENDOPLASMIC RETICULUM. It consists of a group of regulatory cascades that are triggered as a response to altered levels of calcium and/or the redox state of the endoplasmic reticulum. Persistent activation of the unfolded protein response leads to the induction of APOPTOSIS. MeSH
Hierarchy View
Subtype Terms (1)
Hierarchy Tree View
YOU AGREE THAT THE INFORMATION PROVIDED ON THIS WEBSITE IS PROVIDED “AS IS”, WITHOUT ANY WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING WITHOUT LIMITATION WARRANTIES OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE, OR NON-INFRINGEMENT OF ANY THIRD-PARTY PATENT, COPYRIGHT, OR ANY OTHER THIRD-PARTY RIGHT. IN NO EVENT SHALL THE CREATORS OF THE WEBSITE OR WASHINGTON UNIVERSITY BE LIABLE FOR ANY DIRECT, INDIRECT, SPECIAL, OR CONSEQUENTIAL DAMAGES ARISING OUT OF OR IN ANY WAY CONNECTED WITH THE WEBSITE, THE USE OF THE WEBSITE, OR THIS AGREEMENT, WHETHER IN BREACH OF CONTRACT, TORT OR OTHERWISE, EVEN IF SUCH PARTY IS ADVISED OF THE POSSIBILITY OF SUCH DAMAGES.
