Jumonji Domain-Containing Histone Demethylases D056484

Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Oxidoreductases » Oxidoreductases Acting on CH-NH Group Donors » Oxidoreductases, N-Demethylating » Histone Demethylases » Jumonji Domain-Containing Histone Demethylases

Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Oxidoreductases » Oxygenases » Dioxygenases » Jumonji Domain-Containing Histone Demethylases

Description

A family of histone demethylases that share a conserved Jumonji C domain. The enzymes function via an iron-dependent dioxygenase mechanism that couples the conversion of 2-oxoglutarate to succinate to the hydroxylation of N-methyl groups.   MeSH

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