Phenomena and Processes [G] » Chemical Phenomena [G02] » Biochemical Phenomena » Molecular Structure » Molecular Conformation » Nucleic Acid Conformation » G-Quadruplexes
Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Structures » Nucleic Acid Conformation » G-Quadruplexes
Description
Higher-order DNA and RNA structures formed from guanine-rich sequences. They are formed around a core of at least 2 stacked tetrads of hydrogen-bonded GUANINE bases. They can be formed from one two or four separate strands of DNA (or RNA) and can display a wide variety of topologies, which are a consequence of various combinations of strand direction, length, and sequence. (From Nucleic Acids Res. 2006;34(19):5402-15) MeSH
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