Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Peptides, Cyclic » Echinocandins
Description
Cyclic hexapeptides of proline-ornithine-threonine-proline-threonine-serine. The cyclization with a single non-peptide bond can lead them to be incorrectly called DEPSIPEPTIDES, but the echinocandins lack ester links. Antifungal activity is via inhibition of 1,3-beta-glucan synthase production of BETA-GLUCANS. MeSH
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