Related MeSH Hierarchy (6)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Intercellular Signaling Peptides and Proteins » Cytokines » Transforming Growth Factor beta » Transforming Growth Factor beta2
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Intercellular Signaling Peptides and Proteins » TGF-beta Superfamily Proteins » Transforming Growth Factor beta » Transforming Growth Factor beta2
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intercellular Signaling Peptides and Proteins » Cytokines » Transforming Growth Factor beta » Transforming Growth Factor beta2
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intercellular Signaling Peptides and Proteins » TGF-beta Superfamily Proteins » Transforming Growth Factor beta » Transforming Growth Factor beta2
Chemicals and Drugs [D] » Biological Factors [D23] » Intercellular Signaling Peptides and Proteins » Cytokines » Transforming Growth Factor beta » Transforming Growth Factor beta2
Chemicals and Drugs [D] » Biological Factors [D23] » Intercellular Signaling Peptides and Proteins » TGF-beta Superfamily Proteins » Transforming Growth Factor beta » Transforming Growth Factor beta2
Description
A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. MeSH
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