Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Peptide Hydrolases » Endopeptidases » Metalloendopeptidases » Matrix Metalloproteinases » Matrix Metalloproteinases, Membrane-Associated » Matrix Metalloproteinase 14
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Peptide Hydrolases » Metalloproteases » Metalloendopeptidases » Matrix Metalloproteinases » Matrix Metalloproteinases, Membrane-Associated » Matrix Metalloproteinase 14
Description
A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the action of PROPROTEIN CONVERTASES such as FURIN. Matrix metalloproteinase 14 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of MATRIX METALLOPROTEINASE 15. MeSH
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