Related MeSH Hierarchy (7)
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Transferases » Phosphotransferases » Phosphotransferases (Alcohol Group Acceptor) » Protein Kinases » Protein Serine-Threonine Kinases » Receptor-Interacting Protein Serine-Threonine Kinases
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » Adaptor Proteins, Signal Transducing » Death Domain Receptor Signaling Adaptor Proteins » Receptor-Interacting Protein Serine-Threonine Kinases
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » Adaptor Proteins, Signal Transducing » Tumor Necrosis Factor Receptor-Associated Peptides and Proteins » Receptor-Interacting Protein Serine-Threonine Kinases
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Adaptor Proteins, Signal Transducing » Death Domain Receptor Signaling Adaptor Proteins » Receptor-Interacting Protein Serine-Threonine Kinases
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Adaptor Proteins, Signal Transducing » Tumor Necrosis Factor Receptor-Associated Peptides and Proteins » Receptor-Interacting Protein Serine-Threonine Kinases
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Apoptosis Regulatory Proteins » Death Domain Receptor Signaling Adaptor Proteins » Receptor-Interacting Protein Serine-Threonine Kinases
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Protein Serine-Threonine Kinases » Receptor-Interacting Protein Serine-Threonine Kinases
Description
A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment. MeSH
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