Related MeSH Hierarchy (8)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Intracellular Signaling Peptides and Proteins » Apoptosis Regulatory Proteins » Death Domain Receptor Signaling Adaptor Proteins » Edar-Associated Death Domain Protein
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » Adaptor Proteins, Signal Transducing » Death Domain Receptor Signaling Adaptor Proteins » Edar-Associated Death Domain Protein
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » Adaptor Proteins, Signal Transducing » Tumor Necrosis Factor Receptor-Associated Peptides and Proteins » Edar-Associated Death Domain Protein
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Adaptor Proteins, Signal Transducing » Death Domain Receptor Signaling Adaptor Proteins » Edar-Associated Death Domain Protein
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Adaptor Proteins, Signal Transducing » Tumor Necrosis Factor Receptor-Associated Peptides and Proteins » Edar-Associated Death Domain Protein
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Apoptosis Regulatory Proteins » Death Domain Receptor Signaling Adaptor Proteins » Edar-Associated Death Domain Protein
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Intracellular Signaling Peptides and Proteins » Adaptor Proteins, Signal Transducing » Death Domain Receptor Signaling Adaptor Proteins » Edar-Associated Death Domain Protein
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Intracellular Signaling Peptides and Proteins » Adaptor Proteins, Signal Transducing » Tumor Necrosis Factor Receptor-Associated Peptides and Proteins » Edar-Associated Death Domain Protein
Description
A tumor necrosis factor receptor-associated factor that acts as a specific signaling adaptor protein for the EDAR RECEPTOR and plays an important role in ectodermal development. It binds to edar receptor via its C-terminal death domain region and to other specific TNF receptor-associated factors via its N-terminal domain. Loss of function of edar-associated death domain protein is associated with AUTOSOMAL RECESSIVE ANHIDROTIC ECTODERMAL DYSPLASIA. MeSH
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