Chemicals and Drugs [D] » Lipids [D10] » Lipoproteins » Lipoprotein(a) » Apoprotein(a)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Lipoproteins » Lipoprotein(a) » Apoprotein(a)
Description
A large and highly glycosylated protein constituent of LIPOPROTEIN (A). It has very little affinity for lipids but forms disulfide-linkage to APOLIPOPROTEIN B-100. Apoprotein(a) has SERINE PROTEINASE activity and can be of varying sizes from 400- to 800-kDa. It is homologous to PLASMINOGEN and is known to modulate THROMBOSIS and FIBRINOLYSIS. MeSH
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