Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Fanconi Anemia Complementation Group Proteins » Fanconi Anemia Complementation Group D2 Protein
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Nuclear Proteins » Fanconi Anemia Complementation Group D2 Protein
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Phosphoproteins » Fanconi Anemia Complementation Group D2 Protein
Description
A Fanconi anemia complementation group protein that undergoes mono-ubiquitination by FANCL PROTEIN in response to DNA DAMAGE. Also, in response to IONIZING RADIATION it can undergo PHOSPHORYLATION by ataxia telangiectasia mutated protein. Modified FANCD2 interacts with BRCA2 PROTEIN in a stable complex with CHROMATIN, and it is involved in DNA REPAIR by homologous RECOMBINATION. MeSH
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