Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Transferases » Acyltransferases » Acetyltransferases » Lysine Acetyltransferases » Histone Acetyltransferases » p300-CBP Transcription Factors
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Transcription Factors » p300-CBP Transcription Factors
Description
A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription machinery. They also modify transcription factors and CHROMATIN through ACETYLATION. MeSH
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