Related MeSH Hierarchy (5)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Intracellular Signaling Peptides and Proteins » Adaptor Proteins, Signal Transducing » Interferon-Stimulated Gene Factor 3
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » Adaptor Proteins, Signal Transducing » Interferon-Stimulated Gene Factor 3
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » DNA-Binding Proteins » Interferon-Stimulated Gene Factor 3
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Adaptor Proteins, Signal Transducing » Interferon-Stimulated Gene Factor 3
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Transcription Factors » Interferon-Stimulated Gene Factor 3
Description
A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES. MeSH
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