Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Intracellular Signaling Peptides and Proteins » Adaptor Proteins, Signal Transducing » STAT Transcription Factors » STAT3 Transcription Factor
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » Adaptor Proteins, Signal Transducing » STAT Transcription Factors » STAT3 Transcription Factor
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Adaptor Proteins, Signal Transducing » STAT Transcription Factors » STAT3 Transcription Factor
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Transcription Factors » STAT Transcription Factors » STAT3 Transcription Factor
Description
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130. MeSH
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