Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Oxidoreductases » Alcohol Oxidoreductases » Hydroxysteroid Dehydrogenases » 3-Hydroxysteroid Dehydrogenases » 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Oxidoreductases » Alcohol Oxidoreductases » NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases » 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)
Description
A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has activity towards other 3-alpha-hydroxysteroids and on 9-, 11- and 15- hydroxyprostaglandins. The enzyme is B-specific in reference to the orientation of reduced NAD or NADPH. MeSH
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