Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » DNA Repair Enzymes » DNA-(Apurinic or Apyrimidinic Site) Lyase
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Lyases » Carbon-Oxygen Lyases » DNA-(Apurinic or Apyrimidinic Site) Lyase
Description
A DNA repair enzyme that catalyses the excision of ribose residues at apurinic and apyrimidinic DNA sites that can result from the action of DNA GLYCOSYLASES. The enzyme catalyzes a beta-elimination reaction in which the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. This enzyme was previously listed under EC 3.1.25.2. MeSH
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