Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Protein-Tyrosine Kinases » Receptor Protein-Tyrosine Kinases » Receptors, Vascular Endothelial Growth Factor » Vascular Endothelial Growth Factor Receptor-1
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Transferases » Phosphotransferases » Phosphotransferases (Alcohol Group Acceptor) » Protein Kinases » Protein-Tyrosine Kinases » Receptor Protein-Tyrosine Kinases » Receptors, Vascular Endothelial Growth Factor » Vascular Endothelial Growth Factor Receptor-1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Receptors, Cell Surface » Receptor Protein-Tyrosine Kinases » Receptors, Vascular Endothelial Growth Factor » Vascular Endothelial Growth Factor Receptor-1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Receptors, Cell Surface » Receptors, Peptide » Receptors, Growth Factor » Receptors, Vascular Endothelial Growth Factor » Vascular Endothelial Growth Factor Receptor-1
Description
A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction. MeSH
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