Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » Calcium-Binding Proteins » S100 Proteins » Leukocyte L1 Antigen Complex
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Surface » Leukocyte L1 Antigen Complex
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Nerve Tissue Proteins » S100 Proteins » Leukocyte L1 Antigen Complex
Description
A member of the S-100 protein family that is present at high levels in the blood and interstitial fluid in several infectious, inflammatory, and malignant disorders, including rheumatoid arthritis, inflammatory bowel disease, and cystic fibrosis. It is a complex of a light chain (CALGRANULIN A) and a heavy chain (CALGRANULIN B). L1 binds calcium through an EF-hand motif, and has been shown to possess antimicrobial activity. MeSH
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