Chemicals and Drugs [D] » Hormones, Hormone Substitutes, and Hormone Antagonists [D06] » Hormones » Peptide Hormones » Gonadotropins » Gonadotropins, Pituitary » Luteinizing Hormone » Luteinizing Hormone, beta Subunit
Chemicals and Drugs [D] » Hormones, Hormone Substitutes, and Hormone Antagonists [D06] » Hormones » Peptide Hormones » Pituitary Hormones » Pituitary Hormones, Anterior » Gonadotropins, Pituitary » Luteinizing Hormone » Luteinizing Hormone, beta Subunit
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Peptide Hormones » Pituitary Hormones » Pituitary Hormones, Anterior » Gonadotropins, Pituitary » Luteinizing Hormone » Luteinizing Hormone, beta Subunit
Description
The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility. MeSH
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