Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » RNA-Binding Proteins » RNA Recognition Motif Proteins » Heterogeneous-Nuclear Ribonucleoproteins » Heterogeneous-Nuclear Ribonucleoprotein K
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » DNA-Binding Proteins » Heterogeneous-Nuclear Ribonucleoprotein K
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Nucleoproteins » RNA-Binding Proteins » RNA Recognition Motif Proteins » Heterogeneous-Nuclear Ribonucleoproteins » Heterogeneous-Nuclear Ribonucleoprotein K
Description
A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties. MeSH
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