Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Isomerases » DNA Topoisomerases » DNA Topoisomerases, Type II » DNA Topoisomerase IV
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Bacterial Proteins » DNA Topoisomerase IV
Description
A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication. MeSH
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