Phenomena and Processes [G] » Chemical Phenomena [G02] » Biochemical Phenomena » RNA Processing, Post-Transcriptional » RNA 3' End Processing » Polyadenylation
Phenomena and Processes [G] » Metabolism [G03] » RNA Processing, Post-Transcriptional » RNA 3' End Processing » Polyadenylation
Phenomena and Processes [G] » Genetic Phenomena [G05] » Gene Expression Regulation » RNA Processing, Post-Transcriptional » RNA 3' End Processing » Polyadenylation
Description
The addition of a tail of polyadenylic acid (POLY A) to the 3' end of mRNA (RNA, MESSENGER). Polyadenylation involves recognizing the processing site signal, (AAUAAA), and cleaving of the mRNA to create a 3' OH terminal end to which poly A polymerase (POLYNUCLEOTIDE ADENYLYLTRANSFERASE) adds 60-200 adenylate residues. The 3' end processing of some messenger RNAs, such as histone mRNA, is carried out by a different process that does not include the addition of poly A as described here. MeSH
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