Complementarity Determining Regions D022801

Related MeSH Hierarchy (9)

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Blood Proteins » Immunoproteins » Immunoglobulins » Immunoglobulin Variable Region » Complementarity Determining Regions

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Blood Proteins » Serum Globulins » Immunoglobulins » Immunoglobulin Variable Region » Complementarity Determining Regions

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Globulins » Serum Globulins » Immunoglobulins » Immunoglobulin Variable Region » Complementarity Determining Regions

Phenomena and Processes [G] » Chemical Phenomena [G02] » Biochemical Phenomena » Molecular Structure » Amino Acid Sequence » Immunoglobulin Variable Region » Complementarity Determining Regions

Description

Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin chains form a surface that is complementary to the antigen. These regions are also present in other members of the immunoglobulin superfamily, for example, T-cell receptors (RECEPTORS, ANTIGEN, T-CELL).   MeSH

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