Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Neuropeptides » omega-Agatoxin IVA
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Arthropod Proteins » Agatoxins » omega-Agatoxin IVA
Chemicals and Drugs [D] » Complex Mixtures [D20] » Venoms » Arthropod Venoms » Spider Venoms » Agatoxins » omega-Agatoxin IVA
Chemicals and Drugs [D] » Biological Factors [D23] » Toxins, Biological » Venoms » Arthropod Venoms » Spider Venoms » Agatoxins » omega-Agatoxin IVA
Description
A neuropeptide toxin from the venom of the funnel web spider, Agelenopsis aperta. It inhibits CALCIUM CHANNELS, P-TYPE by altering the voltage-dependent gating so that very large depolarizations are needed for channel opening. It also inhibits CALCIUM CHANNELS, Q-TYPE. MeSH
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