Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Peptide Hydrolases » Cysteine Proteases » Cysteine Endopeptidases » Caspases » Caspases, Initiator » Caspase 1
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Peptide Hydrolases » Endopeptidases » Cysteine Endopeptidases » Caspases » Caspases, Initiator » Caspase 1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Apoptosis Regulatory Proteins » Caspases » Caspases, Initiator » Caspase 1
Description
A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE. MeSH
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