Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Heterocyclic Compounds, 1-Ring » Pyrans » Benzopyrans » Chromones » Flavonoids » Isoflavones » Genistein
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Heterocyclic Compounds, Fused-Ring » Heterocyclic Compounds, 2-Ring » Benzopyrans » Chromones » Flavonoids » Isoflavones » Genistein
Description
An isoflavonoid derived from soy products. It inhibits PROTEIN-TYROSINE KINASE and topoisomerase-II (DNA TOPOISOMERASES, TYPE II); activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 PHASE arrest in human and murine cell lines and inhibits PROTEIN-TYROSINE KINASE. MeSH
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