Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Recombinant Proteins » Vaccines, Synthetic » Nucleic Acid-Based Vaccines » Vaccines, DNA
Chemicals and Drugs [D] » Complex Mixtures [D20] » Biological Products » Vaccines » Vaccines, Synthetic » Nucleic Acid-Based Vaccines » Vaccines, DNA
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Vaccines, Synthetic » Nucleic Acid-Based Vaccines » Vaccines, DNA
Description
Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers. MeSH
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