Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Structures » Genome » Genome Components » Genes » Genes, Neoplasm » Genes, Tumor Suppressor » Genes, BRCA1
Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Structures » Genome » Genome Components » Genes » Genes, Recessive » Genes, Tumor Suppressor » Genes, BRCA1
Description
A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human CHROMOSOME 17 at locus 17q21. Mutations of this gene are associated with the formation of HEREDITARY BREAST AND OVARIAN CANCER SYNDROME. It encodes a large nuclear protein that is a component of DNA repair pathways. MeSH
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