Phenomena and Processes [G] » Chemical Phenomena [G02] » Biochemical Phenomena » Molecular Structure » Base Sequence » GC Rich Sequence » CpG Islands
Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Structures » Base Sequence » GC Rich Sequence » CpG Islands
Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Structures » Genome » Genome Components » CpG Islands
Description
Areas of increased density of the dinucleotide sequence cytosine--phosphate diester--guanine. They form stretches of DNA several hundred to several thousand base pairs long. In humans there are about 45,000 CpG islands, mostly found at the 5' ends of genes. They are unmethylated except for those on the inactive X chromosome and some associated with imprinted genes. MeSH
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