Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Structures » Genetic Code » Codon » Codon, Terminator » Codon, Nonsense
Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Variation » Mutation » Codon, Nonsense
Chemicals and Drugs [D] » Nucleic Acids, Nucleotides, and Nucleosides [D13] » Nucleic Acids » RNA » RNA, Messenger » Codon » Codon, Terminator » Codon, Nonsense
Description
An amino acid-specifying codon that has been converted to a stop codon (CODON, TERMINATOR) by mutation. Its occurance is abnormal causing premature termination of protein translation and results in production of truncated and non-functional proteins. A nonsense mutation is one that converts an amino acid-specific codon to a stop codon. MeSH
Hierarchy View
Phase 2 Indicated Drugs (1)
Hierarchy Tree View
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