Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Receptors, Cell Surface » Receptors, Immunologic » Receptors, Cytokine » Receptors, Tumor Necrosis Factor » Ki-1 Antigen
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Neoplasm » Ki-1 Antigen
Chemicals and Drugs [D] » Biological Factors [D23] » Biomarkers » Biomarkers, Tumor » Ki-1 Antigen
Description
A member of the tumor necrosis factor receptor superfamily that may play a role in the regulation of NF-KAPPA B and APOPTOSIS. It is found on activated T-LYMPHOCYTES; B-LYMPHOCYTES; NEUTROPHILS; EOSINOPHILS; MAST CELLS and NK CELLS. Overexpression of the Ki-1 antigen in hematopoietic malignancies make it clinically useful as a biological tumor marker. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS. MeSH
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